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How does the Cortisol Blood Test Assess Your Stress Hormones?
How does the Cortisol Blood Test Assess Your Stress Hormones?

How does the Cortisol Blood Test Assess Your Stress Hormones?

May 6, 2025

Cortisol, or the ‘stress hormone‘, is responsible for regulating your body’s response to stress. Cortisol controls various functions such as the immune response, blood pressure, and metabolism. It is important to monitor cortisol levels for overall health maintenance since a hormonal imbalance can be responsible for serious health complications.

Private Blood Tests London provides a cortisol blood test in an accurate and convenient way to assess your cortisol levels. This test offers vital insights into how your body deals with stress, allowing you to take proactive steps to improve and manage your health.

What is cortisol?

The adrenal glands secrete cortisol, which is vital in various body functions like immune response, blood pressure regulation, and metabolism. It is essential in enabling the body to react to stressful conditions and maintaining overall health.

When the body faces some threat, the hypothalamus sends signals to the adrenal glands to produce cortisol, triggering the ‘fight or flight’ response. This response is crucial for preparing your body to react promptly to threats by elevating the blood sugar levels, enhancing the use of glucose by the brain, and suppressing other non-essential functions like immune responses and digestion at the moment.

However, chronic stress might result in consistently high cortisol levels which produce adverse effects on health. Prolonged high cortisol levels might lead to high blood pressure, weight gain, a weakened immune system, and disrupted sleep. On the contrary, low cortisol levels might be an indicator of conditions like Addison’s disease characterised by muscle weakness, low blood pressure, and fatigue.

Normal Cortisol Levels

The natural circadian rhythm of your body causes your blood cortisol levels to vary throughout the day. Normal cortisol levels typically range as follows:

  • 10 to 20 mcg/dL or 140 to 690 nmol/L in the morning, between 6 AM and 8 AM
  • 3 to 10 mcg/dL or 80 to 270 nmol/L in the afternoon, around 4 PM

The cortisol levels reach their peak early in the morning which helps you wake up and then decline gradually throughout the day, attaining the lowest point during midnight.

What factors influence cortisol levels?

A number of issues like exercise, stress, and some drugs influence cortisol levels. It is necessary to adhere to all preparation guidelines provided by your physician.

This might include avoiding strenuous exercise the day prior to the cortisol test, and temporarily stopping certain medications that may affect cortisol levels. Some of these drugs include hormonal therapies and corticosteroids.

What do abnormal cortisol levels signify?

High Cortisol Levels (Hypercortisolism)

Elevated cortisol levels could indicate conditions such as Cushing’s syndrome, in which too much cortisol is secreted by your body. The most frequent causes are occurrence of tumours on pituitary or adrenal glands, persistent stress, or long-term exposure to corticosteroid medications. High cortisol levels may produce symptoms like high blood sugar, high blood pressure, and weight gain.

How can you spot high cortisol levels?

Hypercortisolism or high cortisol levels can result in different health complications. Detecting these symptoms early can help effective heath management. General signs of high cortisol are:

  • Weight gain: Typically on the face, upper back, and abdomen.
  • High blood pressure: Regular increase in blood pressure.
  • Mood shifts: Worsening of irritability, depression, or anxiety.
  • Muscle weakness: Fatigue and overall muscle weakness.
  • High blood sugar: High blood sugar levels, eventually leading to diabetes.
  • Skin changes: Easy bruising of thin and fragile skin, resulting in slow recovery from infections or even minor cuts.

Low Cortisol Levels (Hypocortisolism)

When your adrenal glands do not produce adequate cortisol, low cortisol can lead to conditions like Addison’s disease. Prolonged use of corticosteroid medications or an underactive pituitary gland can lead to low cortisol levels. These are characterised by muscle weakness, low blood pressure, and fatigue.

How can you spot low cortisol levels?

Low cortisol levels can be responsible for significantly affecting your health. Recognising its symptoms allow timely intervention. Some of its common signs are:

  • Fatigue: Constant tiredness even after adequate rest.
  • Muscle weakness: Difficulty in performing various physical activities because of general weakness.
  • Weight loss: Loss of appetite along with unexplained weight loss.
  • Low blood pressure: Light headedness and dizziness due to low blood pressure.
  • Vomiting and nausea: Digestive problems such as abdominal pain and nausea.
  • Salt cravings: Unusual cravings for salty foods.

How does stress affect cortisol levels?

Once you encounter a stressful situation, the hypothalamic-pituitary-adrenal (HPA) axis is triggered by your body, leading to release of cortisol. Although cortisol is important for handling situations of acute stress, chronic stress might lead to high cortisol, disrupting several body functions.

How to manage stress for maintaining healthy cortisol levels?

Proper stress management is essential for attaining optimal cortisol levels, and here are some of its strategies:

  • Regular exercise: Regular physical activity can lower stress and reduce cortisol levels.
  • Healthy diet: Balanced nutrition is vital for your stress and overall health management.
  • Adequate sleep: Sufficient rest is crucial for regulating your cortisol production.
  • Relaxation techniques: Practices such as meditation, deep breathing exercises, and yoga can reduce your stress to a significant level.
  • Social support: Staying in touch with family, relatives, and friends can offer the necessary emotional support to lower your stress.
  • Professional help: Consulting a therapist or healthcare provider helps you adapt strategies to manage and cope with chronic stress.

If stress is affecting your health, a cortisol blood test can give you answers. Ask your doctor if testing is right for you.

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Why is cortisol blood test important?

Assessing cortisol levels through a blood test allows you to understand and manage several health conditions associated with adrenal function and stress. Here are the reasons why you should get a cortisol blood test:

  • Diagnosing health conditions

Abnormal cortisol levels might point to several health complications. While persistently high cortisol levels indicate Cushing’s syndrome, low cortisol levels are responsible for causing Addison’s disease.

  • Monitoring stress and its impacts

Cortisol works as a key marker in determining how your body deals with stress. Chronic stress might result in long term high cortisol levels, producing adverse effects on your overall health. Regular monitoring can help the body manage stress and chalk out necessary lifestyle adjustments.

  • Guiding treatment plans

Individuals going through treatments of adrenal gland disorders and related issues, regular cortisol tests allow making adjustments in your medications for ensuring treatments are proceeding effectively. This helps monitor the improvements in your cortisol levels as the treatment progresses.

Book Your Cortisol Blood Test Today

Monitoring cortisol levels on a regular basis through a blood test is vital for overall health maintenance and effective stress management. Being aware of your cortisol levels helps early detection of potential health issues, allowing you to make informed lifestyle decisions and optimising your wellbeing.

At Private Blood Tests London, we offer reliable and convenient cortisol blood testing at our clinic, providing fast and accurate results without the need for referrals. We, in conjunction with accredited laboratories, ensure quick and accurate test results, enabling you to take proactive approaches towards better health and wellbeing without the hassle of long waiting durations or referrals. Book an appointment with us to extract crucial insights into how your body deals with stress.

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