What is cortisol testing?
Testing for cortisol measures the level of cortisol in your body through the bloodstream, saliva, or urine. Cortisol, often called the “stress hormone,” is a vital hormone produced by the adrenal glands above your kidneys. It plays a critical role in:
- Inflammation Reduction: Minimises inflammation in the body.
- Stress Response: Helps your body react to stress.
- Blood Pressure Control: Maintains normal blood pressure levels.
- Metabolism Regulation: Manages how your body converts food into energy and regulates blood sugar.
The pituitary gland in the brain controls cortisol production. If cortisol levels are too high or too low, it may indicate an adrenal gland disorder, an issue with the pituitary gland, or a tumour producing excess cortisol.
Other Names for Cortisol Testing
- Plasma Cortisol
- Urinary Cortisol
- Free Cortisol
- Blood Cortisol
- Salivary Cortisol
Causes of abnormal cortisol levels
- Low Levels: Abruptly stopping steroid medications.
- Elevated Levels: Prolonged use of high-dose steroid medications like prednisone.
If left untreated, excessively high or low cortisol levels can lead to serious health conditions.
Why do you need a cortisol test?
The test helps assess whether the adrenal gland produces adequate cortisol. It is useful in monitoring and diagnosing various health problems, including:
- Cushing’s Syndrome: A condition caused by excessively high levels of cortisol.
- Cushing’s Disease: A form of Cushing’s Syndrome linked to elevated ACTH (adrenocorticotropic hormone), which triggers excessive cortisol production.
- Addison’s Disease: A disorder causing insufficient production of hormones, including cortisol.
When is cortisol testing recommended?
Your healthcare provider may suggest a cortisol test if you exhibit symptoms of a condition affecting levels of cortisol, such as:
Symptoms of low levels of cortisol (Addison’s disease):
- Low blood pressure.
- Vomiting, nausea, or diarrhoea.
- Persistent fatigue.
- Dark patches on the skin, lips, and gums.
- Weight loss and appetite reduction.
- Abdominal pain and muscle weakness.
- Craving salty foods.
Symptoms of high levels of cortisol (Cushing’s syndrome):
- Thin arms and legs.
- Mood swings and weakened bones.
- Unexplained weight gain, particularly in children.
- Slow-healing wounds.
- Round, red face.
- Purple stretch marks on the abdomen.
- Increased body hair or balding.
- High blood pressure.
- Fat deposits around the neck or between the shoulders.
In some cases, cortisol testing is also used to evaluate the effectiveness of a treatment for individuals managing abnormal cortisol levels.
Who needs to undergo cortisol testing?
Doctors may recommend this test for:
- Patients with adrenal tumours detected during imaging.
- Individuals with unusual health conditions, such as hypertension or osteoporosis, at a young age.
- Those experiencing severe symptoms suggesting adrenal gland dysfunction.
Cost of a cortisol test
The cost of a cortisol test depends on factors such as:
- Whether the test is conducted alongside other diagnostic procedures.
- Type of test (blood, saliva, or urine).
- Testing location and facility.
Additional costs may include laboratory analysis fees, phlebotomy charges, or office consultation fees. If you have private health insurance, check your coverage for cortisol testing. Many clinics offer cost-reduction programmes for uninsured individuals—consult your healthcare provider for further details.
Book Your Cortisol Test Today!
If you are experiencing symptoms of abnormal cortisol levels or your doctor has advised testing, contact us at Private Blood Tests London today. Arrange an appointment to ensure timely diagnosis and management of this condition.
How Private Blood Tests London Works

Order your test
Select the test that you would like to undergo

Provide your sample
Go to the Harley Street clinic for your blood draw and pay for your test in person

View your results
As soon as the results are ready, the will be sent to you by your chosen method

World class partner lab

Advice from expert UK doctors
